Printable ADA-GEL-based composite inks containing Zn-doped bioactive inorganic fillers for skeletal muscle biofabrication.

Bioprinting shows significant promise in advancing medical treatments by offering patient-specific solutions for repairing skeletal muscle tissues. Zinc (Zn) is one of the key ions in the human body involved in the development of myogenic cells. This study investigates the integration of Zn-doped bioactive inorganic fillers (BIFs) into alginate-dialdehyde-gelatin (ADA-GEL) as composite ink for bioprinting applications.

Preparation of tricalcium phosphate/calcium pyrophosphate structures via rapid prototyping.

Custom made tricalcium phosphate/calcium pyrophosphate bone substitutes with a well-defined architecture were fabricated in this study using 3D powder printing with tricalcium phosphate (TCP) powder and a liquid phase of phosphoric acid. The primary formed matrix of dicalcium phosphate dihydrate (DCPD, brushite) was converted in a second step to calcium pyrophosphate (CPP) by heat treatment in the temperature range 1,100-1,300 degrees C. The structures exhibited compressive strengths between 0.