Publications by authors named "Isabela Maria Santiago-Jaegger"
Objective: This study aimed to assess the effects of fluoxetine, a selective serotonin reuptake inhibitor, on the formation of the periodontal ligament during pregnancy and lactation in rat pups.
Material And Methods: Twelve pregnant rats of Wistar lineage were divided into four study groups. In the control group, 0.
Article Synopsis
- The study aimed to investigate the effects of fluoxetine on mandibular bone formation in rats during pregnancy and lactation.
- It involved 24 Wistar rat pups divided into four groups, with some receiving fluoxetine during gestation and/or lactation, and various analyses were conducted on their mandibles at 25 days old.
- Results indicated that fluoxetine treatment led to reductions in mandibular bone mass, including decreased thickness, fewer osteocytes, and lower bone density, particularly in those treated during both gestation and lactation.