Publications by authors named "Isabel Yaguee Lobo"

Background: The impact caused by the coronavirus disease 2019 (COVID-19) on the Portuguese population has been addressed in areas such as clinical manifestations, frequent comorbidities, and alterations in consumption habits. However, comorbidities like liver conditions and changes concerning the Portuguese population's access to healthcare-related services have received less attention.

Aim: To (1) Review the impact of COVID-19 on the healthcare system; (2) examine the relationship between liver diseases and COVID-19 in infected individuals; and (3) investigate the situation in the Portuguese population concerning these topics.

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  • The study examined fluid resuscitation practices in Brazilian intensive care units and compared them to those in 27 other countries as part of the Fluid-TRIPS project.
  • On the study day, a significantly lower percentage of patients in Brazil (16.1%) received fluids compared to patients in other countries (26.8%), with a higher emphasis on crystalloids, particularly sodium chloride (0.9%).
  • Factors influencing fluid choice included patient serum albumin levels and the type of healthcare provider prescribing the fluids.
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  • - The study reviews the impact of the COVID-19 pandemic on globally heightened anxiety levels, finding that 25% of the general population reported anxiety during this period, compared to the typical 7.3% pre-pandemic rate.
  • - Researchers analyzed data from 43 studies published between December 2019 and August 2020, identifying several risk factors for anxiety such as social isolation, unemployment, and low knowledge about the virus.
  • - These results indicate a significant deterioration in mental health due to the pandemic, highlighting the need for targeted strategies to address these anxiety levels in individuals and communities.
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  • The research investigates the levels of anxiety in medical students during the COVID-19 pandemic, finding an overall prevalence of 28%.
  • Anxiety rates remained stable in medical students compared to non-medical peers, possibly due to their knowledge about COVID-19, which helps mitigate stress.
  • A notable limitation is that the majority of included studies focused on Chinese medical students, raising concerns about how well these findings apply to medical students globally.
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  • - The study aimed to investigate whether hip fracture risk is affected differently by cognitive impairment in men and women, and to examine the links between mild cognitive impairment (MCI) and mild neurocognitive disorder (MND).
  • - An analysis of 4,803 individuals aged 55+ in Zaragoza, Spain, over 16 years revealed that men face a significantly higher risk of hip fractures at "mild" and "severe" cognitive impairment stages, but no similar association was found in women.
  • - Results showed that men exhibited increased hip fracture risk at mild (HR=4.99) and severe (HR=9.31) cognitive impairment levels, while no substantial correlations were present for women or between hip fractures
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The objective of this study is to investigate cognitive performance in a first-episode psychosis sample, when stratifying the interaction by cannabis use and familial or non-familial psychosis. Hierarchical-regression models were used to analyse this association in a sample of 268 first-episode psychosis patients and 237 controls. We found that cannabis use was associated with worse working memory, regardless of family history.

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Rationale: Severe community-acquired pneumonia (sCAP) is a leading cause of death worldwide. Adjunctive therapies for sCAP are needed to further improve outcome. A systemic inhibitor of coagulation, tifacogin (recombinant human tissue factor pathway inhibitor) seemed to provide mortality benefit in the sCAP subgroup of a previous sepsis trial.

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