Publications by authors named "Isabel Santos-Sanchez"

Article Synopsis
  • The study investigates whether early intensive lipid-lowering therapy can help achieve lower LDL cholesterol levels in patients who have suffered an acute myocardial infarction (AMI).
  • It evaluates the effectiveness of a combination therapy (high-potency statin, bempedoic acid, and ezetimibe) compared to standard guideline-recommended treatment on patients at risk for high LDL levels.
  • The primary goal is to see if this intensive treatment can lead to at least 33% of patients reaching LDL levels below 55 mg/dL within 8 weeks after their AMI.
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Aims: Frailty and dependence are frequent in patients admitted for acute heart failure (AHF), but their prognostic significance is unknown, especially in young adults. We aimed to study in adults admitted for AHF, regardless of age, the effect of frailty and dependence on the incidence of mortality and a combined event of mortality, readmissions for AHF, and visits to the emergency room (ER) for AHF at 1 and 6 months.

Methods And Results: We designed a prospective cohort study by including all the patients with AHF admitted in our Cardiology Department from July 2020 through May 2021.

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Background: Heart failure prevalence is increasing in elder adults. These patients usually present geriatric syndromes, especially frailty. The effect of frailty on heart failure is under discussion but there are few data about the clinical characterization of frail patients who are admitted for acute heart failure decompensation.

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Frailty has traditionally been studied in the elderly population but scarcely in younger individuals. The objective of the present study is to analyze differences according to age in the diagnostic performance of cardiac biomarkers to predict frailty in patients admitted to the hospital for acute heart failure (AHF). A frailty assessment was performed with the SPPB and FRAIL scales (score > 3).

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