Growth of a cohort of very low birth weight and preterm infants born at a single tertiary health care center in South Africa.

Background: Very low birth weight (VLBW) and extremely low birth weight (ELBW) infants are known to be at high risk of growth failure and developmental delay later in life. The majority of those infants are born in low and middle income countries.

Aim: Growth monitoring in a cohort of infants born with a VLBW up to 18 months corrected age was conducted in a low resource setting tertiary hospital.

Prospective cohort study of mortality in very low birthweight infants in a single centre in the Eastern Cape province, South Africa.

Background: Neonatal mortality is a major contributor worldwide to the number of deaths in children under 5 years of age. The primary objective of this study was to assess the overall mortality rate of babies with a birth weight equal or below 1500 g in a neonatal unit at a tertiary hospital in the Eastern Cape Province, South Africa. Furthermore, different maternal-related and infant-related factors for higher mortality were analysed.

Late diagnosis of human immunodeficiency virus infection is linked to higher rates of epilepsy in children in the Eastern Cape of South Africa.

Background: Human immunodeficiency virus (HIV)-positive children may present with a wide range of neurological disorders. Among these, epilepsy is of key concern because of its lifelong impact and potential for damage to the central nervous system (CNS). Few studies in developing regions have investigated the prevalence and aetiology of epilepsy in HIV-infected children as a key population.

Plasma exchange is effective in a 13-year-old girl with steroid-resistant bilateral optic neuritis.

We describe a 13-year-old girl presenting with steroid-resistant bilateral optic neuritis. After plasma exchange (PE), the girl experienced full recovery of her visual acuity. During a 4-year follow-up no relapse occurred.