Publications by authors named "Isabel Mantia"
Front Pharmacol
August 2024
Article Synopsis
- Approximately 57.4 million people worldwide are affected by dementia, with behavioral and psychological symptoms (BPSD), particularly agitation, being prevalent and often challenging to manage.
- The BRAINAID trial tested a nanotechnology device, NanoBEO, on 29 elderly patients (65+) with severe dementia to evaluate its effectiveness in reducing agitation and pain, utilizing a randomized and placebo-controlled design.
- Results indicated that NanoBEO significantly reduced agitation levels and frequency by 28% after 4 weeks, and showed notable pain relief (45.46% improvement) after just 1 week, without requiring additional medications.
