Objective: To study ovulation in adolescents with type 1 diabetes (T1D) and the effect of hemoglobin A1c (HbA1c) levels on their ovulatory function.
Design: Prospective investigation.
Setting: Academic research institute.
Aim: To study the adiponectin levels during puberty in girls with type 1 diabetes mellitus (DM1) and their relationship to body mass index (BMI), Tanner stage, ovarian volume (OV), and androgen levels.
Methods: We studied adiponectin and testosterone levels and OV in 56 pubertal girls with DM1 and in 59 healthy girls serving as controls. The effects of DM1, BMI standard deviation scores (BMI SDS), testosterone, and OV over adiponectin levels were assessed.