Broad counseling for adolescents about combined hormonal contraceptive methods: the choice study.

Purpose: The Contraceptive Health Research of Informed Choice Experience study involved 11 European countries with the goal of evaluating the influence of counseling on the user's choice among three different types of combined hormonal contraceptive (CHC) administration: pill, transdermal patch, and vaginal ring. Here, we report the results of the youngest age group (age 15-20 years) for Switzerland.

Methods: A total of 1,032 adolescent women who contemplated a CHC form of contraception were counseled about the three CHCs.

Intention to use a combined contraceptive method and decision after counselling in Switzerland--Swiss data from the European CHOICE study.

Background: Considering the advantages of parenteral routes of administration of combined hormonal contraceptives (CHCs), their low prevalence of use in Europe is surprising. The Contraceptive health research of informed choice experience (CHOICE) study involved 11 European countries. It aimed at evaluating the influence of counselling on users' choice between three modalities of CHC administration (the pill, the transdermal patch, and the vaginal ring).

Cotranslational assembly of the yeast SET1C histone methyltransferase complex.

While probing the role of RNA for the function of SET1C/COMPASS histone methyltransferase, we identified SET1RC (SET1 mRNA-associated complex), a complex that contains SET1 mRNA and Set1, Swd1, Spp1 and Shg1, four of the eight polypeptides that constitute SET1C. Characterization of SET1RC showed that SET1 mRNA binding did not require associated Swd1, Spp1 and Shg1 proteins or RNA recognition motifs present in Set1. RNA binding was not observed when Set1 protein and SET1 mRNA were derived from independent genes or when SET1 transcripts were restricted to the nucleus.

Anatomy of the estrogen response element.

Estrogens exert their regulatory potential on gene expression through different nuclear and non-nuclear mechanisms. A direct nuclear approach is the interaction of estrogen with specific target sequences of DNA, estrogen response elements (ERE) or units. EREs can be grouped into perfect and imperfect palindromic sequences with the imperfect sequences differing from the consensus sequence in one or more nucleotides and being less responsive to the activated estrogen-estrogen receptor (ER) complex.

Physical characteristics of newborn babies after vaginal delivery: a 25-year study from Vienna.

This retrospective analysis evaluated whether the gestational age, mean birth weight, length and shoulder width of vaginally delivered newborns have increased during the last 25 years in Vienna, Austria. Women who have given birth at the University of Vienna Medical School Hospital were divided into four age groups: under 20 years, 20-24 years, 25-29 years, and 30 years of age or over. Patient data collected between 1976 to 2000 were grouped into five periods: 1976-1979, 1980-1984, 1985-1989, 1990-1994, and 1995-2000.