Immunosuppressive Glycodelin A is an independent marker for poor prognosis in endometrial cancer.

Background: Knowledge on immunosuppressive factors in the pathogenesis of endometrial cancer is scarce. The aim of this study was to assess Glycodelin (Gd) and its immunosuppressive isoform Glycodelin A (GdA) in endometrial cancer tissue and to analyze its impact on clinical and pathological features and patient outcome.

Methods: 292 patients diagnosed and treated for endometrial cancer were included.