Publications by authors named "Isabel Lara-Plaza"
The role of aeromonads as contributors to gastrointestinal pathology remains controversial. The aim of this study was to analyse the clinical characteristics and risk factors for the acquisition of an enteric infection by Aeromonas spp. in patients with digestive or nephrological diseases.
View Article and Find Full Text PDFWithin-host transition to GES-55 during a GES-6-producing Serratia marcescens outbreak: Emergence of ceftazidime-avibactam resistance and increased susceptibility to carbapenems.
Sergio García-Fernández Jorge Rodríguez-Grande María Siller-Ruiz Nuria Fraile-Valcárcel Isabel Lara-Plaza
Int J Antimicrob Agents
August 2024
Article Synopsis
- The study tracks the emergence of resistance to ceftazidime-avibactam in a type of antibiotic-resistant bacteria (GES-type carbapenemases) during an unusual outbreak of Serratia marcescens in Spain during COVID-19.* ! -
- Researchers conducted a retrospective analysis using whole genome sequencing to understand the relationships between bacterial samples from patients and their environment, discovering a genetic connection and plasmid transfer related to resistance.* ! -
- Key findings include the appearance of a mutation that facilitated the development of resistance to ceftazidime-avibactam, highlighting the urgent need for improved diagnostic tools and better antimicrobial usage strategies to combat such outbreaks.* !
Article Synopsis
- Candidemia, often linked to medical implants, has seen rising cases of fluconazole-resistant strains in Spain, particularly during the COVID-19 pandemic.
- A study analyzed 1,315 yeast isolates from 2000 to 2021, revealing increased instances of acquired resistance to fluconazole and voriconazole in various Spanish hospitals.
- Three prevalent clones were identified, with a need for further research to understand their expansion and genetic connections.