Measures of Awareness in Alzheimer's Disease and Clinical Differences Between Groups with Preserved, Impaired, and Absent Awareness.

Background: Awareness is a heterogeneous construct that requires accurate assessment. There is no consensus on the best methodology for capturing the phenomenon, thus leading to inconsistent results in this area.

Objective: We aim to evaluate the reliability of clinicians' ratings and a discrepancy assessment method, examining groups of people with Alzheimer's disease (PwAD) according to their degree of awareness and demographic and clinical aspects.

A Longitudinal Evaluation of the Pattern of Social Cognition Impairment in Brazilians With Alzheimer's Disease.

Background: Social cognition (SC) impairments contribute to the dependence of people with Alzheimer disease (AD), influencing their functional disability and the burden on family members and caregivers. Our objective was to longitudinally investigate the relationship between SC and cognitive and clinical variables in persons with AD and their caregivers. We also evaluated the different SC predictors from 3 perspectives: people with AD, caregivers of people with AD, and discrepancy analysis.

Awareness of Disease and Its Domains in Young-onset and Late-onset Dementia: The Role of Executive Function.

Introduction: Executive function (EF) involves a general cognitive process linked to strategic organization and control of complex goal-oriented tasks. In young-onset dementia (YOD), especially Alzheimer's disease, the symptoms that stand out in the initial stage are deficits in attention, visual-spatial function, praxis, and language. The present study aims to investigate what components of EF differ in young and late-onset dementia (LOD) and its impact on awareness and its domains.

Repeated adolescent pregnancy in Brazil from 2015 to 2019.

Objective: The aim of this study was to assess the rate of repeated pregnancy in adolescence and its association with early marriage and education level.

Methods: This is a cross-sectional study conducted by searching the Live Births Data System. The study included all adolescents in the age group 10-19 years with live births from 2015 to 2019 (n=2,405,248), divided into three groups: G1: primiparas; G2: with 1 previous pregnancy; and G3: with two or more previous pregnancies.

Facial Expression Recognition of Emotional Situations in Mild and Moderate Alzheimer's Disease.

Recognizing emotional situations may be impaired in people with Alzheimer's disease (AD). We examined differences in the comprehension of an emotional situation in healthy older controls (HOC) and individuals with mild and moderate AD. cross-sectional study.

Dementia and Mental Health During the COVID-19 Pandemic: A Systematic Review.

Objectives: The COVID-19 pandemic raised significant concerns related to the management of care for people with dementia, but few studies have examined the mental health of older adults with dementia and their caregivers during the pandemic, when compared to other populations. This systematic review thus aims to compare and discuss the impact of the COVID-19 pandemic on people with dementia and on their caregivers' mental health.

Methods: A search was performed in the PubMed/Medline and ISI databases according to the PRISMA methodology.

Patterns of impairment in decision-making capacity in Alzheimer's disease and its relationship with cognitive and clinical variables.

Objectives: To investigate the patterns of impairment in decision-making abilities and their relationship with cognitive and clinical symptoms in people with Alzheimer's disease. We hypothesized that decision-making abilities would not be impaired at the same level and would be related to impairment of global cognition and other clinical symptoms of the disease.

Methods: Using a cross-sectional design, we included a consecutive sample of 102 people with Alzheimer's disease and their respective caregivers.

Increase in fertility rate before the age of 14 in Brazil from 1996 to 2018.

Objective: This study aimed to assess live birth frequency and age-specific fertility rates (ASFR) in the period 1996-2018 and the number of pregnancies at <14 years old in the period 2012-2018.

Methods: This was a cross-sectional study conducted by search on Live Births Data System (SINASC/DATASUS) database.

Results: There was a variation in ASFR in Brazil of 0.

Domains of Awareness in Young and Late Onset Dementia.

Background: There is a lack of research investigating whether there are differences in the domains of awareness according to the age at onset of dementia.

Objective: This study is designed to investigate differences in awareness of cognitive functioning and health condition, functional activity impairments, emotional state, and social functioning and relationships among people with young onset (YOD) and late onset dementia (LOD); and examine associations between awareness and its domains with cognition, functionality, neuropsychiatric symptoms, social and emotional functioning, and quality of life (QoL) in both groups.

Methods: A group of 136 people with dementia and their respective caregivers (YOD = 50 and LOD = 86) were consecutively selected.

COVID-19: challenges for dementia care and research.

The COVID-19 pandemic has raised significant concerns about the management and care for people with dementia and their caregivers. In this context, this work will discuss how social isolation or social distancing caused by the pandemic may impact the clinical management of people with dementia, caregivers' health, and dementia research. The pandemic disrupts all forms of social interaction and may increase the behavioral impairment of people with dementia.

Social cognition: Patterns of impairments in mild and moderate Alzheimer's disease.

Objective: Social cognition (SC) deficits in Alzheimer's Disease (AD) are commonly associated with the progression of the disease, and mainly as a result of global cognition deterioration. We aimed to investigate the relationship between SC, global cognition, and other clinical variables in mild and moderate people with AD and their caregivers. We also investigated the differences between self-reported SC and family caregivers' ratings of SC.

The Relationship between Social Cognition and Executive Functions in Alzheimer's Disease: A Systematic Review.

Introduction: Social Cognition (SC) is a complex construct that reflects a wide variety of implicit and explicit cognitive processes. Many neurocognitive domains are associated with SC and the Executive Function (EF) is the most representative one. We conducted a systematic review aiming at clarifying whether SC impairments are associated with dysfunction on EF in people with Alzheimer Disease (AD).

Adolescent pregnancy trends in the last decade.

Introduction: Teenage pregnancy is a universal phenomenon, with higher prevalence in developing countries. Although there has been a reduction in Brasil since the year 2000, the age-specific fertility rate for this age group remains high.

Objective: To evaluate the frequency of adolescence pregnancy in in Brasil from 2006 to 2015 and its association with the Human Development Index (HDI).

Patterns of discrepancies in different objects of awareness in mild and moderate Alzheimer's disease.

Awareness is considered a heterogeneous and non-linear phenomenon in dementia. We aim to investigate patterns of change of different domains of awareness (awareness of cognitive functioning and health condition, activities of daily living, emotional state, social functioning, and relationships) in people with mild and moderate Alzheimer's disease (AD) and aspects related to each domain. Cross-sectional assessment of dyads of people with AD (PwAD) and caregivers ( = 128; CDR1 = 74, CDR2 = 54).

Awareness of disease in Alzheimer's disease: what do patients realize about their own condition?

We aim to assess different objects of awareness of disease of people with Alzheimer's disease (AD) in mild and moderate stages Semi-structured interviews were conducted with 34 participants with AD and qualitative analyses were used to analyze the participants' reports. Cognitive impairment was the most peserved area of awareness. The participants' explanations were mainly categorized as biological/genetic and psychosocial causes.

Factors Related to Different Objects of Awareness in Alzheimer Disease.

Awareness of deficits is a multidimensional phenomenon described as the ability to acknowledge difficulties and impairments. We investigated whether unawareness affects distinct domains to different degrees and identified the factors related to the awareness impairment in Alzheimer Disease (AD). Using a cross-sectional design, we assessed 89 people with AD (PwAD) and their caregivers.

Caregivers' resilience is independent from the clinical symptoms of dementia.

Resilience is the capacity for successful adaptation when faced with the stress of adversity. We aimed to investigate the relationship between caregivers' resilience and the sociodemographic and clinical factors of people with dementia. Cross-sectional assessment of 58 people with dementia and their caregiver dyads showed that most caregivers were female adult children.

Perception of change in sexual activity in Alzheimer's disease: views of people with dementia and their spouse-caregivers.

Introduction: The onset of Alzheimer's disease (AD) affects couples' relationship. We investigated the perception of change and sexual satisfaction in spouse-caregivers and their partners diagnosed with AD.

Methods: We compared 74 dyads of people with Alzheimer's disease (PwAD)/spouse-caregivers and 21 elderly dyads control.

Quality of life in young onset dementia: an updated systematic review.

Introduction: Young onset dementia (YOD) develops before 65 years of age and has specific age-related adverse consequences for quality of life (QoL). We systematically examined factors related to the QoL of people with YOD and their caregivers.

Method: This systematic review used the PRISMA methodology.