Caged Zn Photolysis in Zebrafish Whole Brains Reveals Subsecond Modulation of Dopamine Uptake.

Free, ionic zinc (Zn) modulates neurotransmitter dynamics in the brain. However, the sub-s effects of transient concentration changes of Zn on neurotransmitter release and uptake are not well understood. To address this lack of knowledge, we have combined the photolysis of the novel caged Zn compound [Zn(DPAdeCageOMe)] with fast scan cyclic voltammetry (FSCV) at carbon fiber microelectrodes in live, whole brain preparations from zebrafish ().