Publications by authors named "Isabel Acosta-Galeana"
The neurodegenerative and inflammatory illnesses of amyotrophic lateral sclerosis and multiple sclerosis were once thought to be completely distinct entities that did not share any remarkable features, but new research is beginning to reveal more information about their similarities and differences. Here, we review some of the pathophysiological features of both diseases and their experimental models: RNA-binding proteins, energy balance, protein transportation, and protein degradation at the molecular level. We make a thorough analysis on TDP-43 and hnRNP A1 dysfunction, as a possible common ground in both pathologies, establishing a potential link between neurodegeneration and pathological immunity.
View Article and Find Full Text PDFWe have carefully read the interesting explanatory comment by Eugene V. Sheval [..
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- Immunostaining is a crucial technique for pinpointing protein locations in cells and tissues by using antibodies with various markers, mainly in immunofluorescence for research and diagnosis.
- The technique has its challenges, such as fixing samples and managing antibody incubation times, which necessitate continual improvements in established protocols.
- This review offers optimized methods for immunofluorescence and introduces a new antibody signal enhancer that boosts detection signals, particularly in cervical cancer and fibrous tissues, making it useful for both seasoned and novice researchers.