Short-term exposure to carbamazepine causes oxidative stress on common carp (Cyprinus carpio).

The aim of this research was to determine the bioconcentration factor and if subacute exposure to carbamazepine (2 mg L) modifies the oxidative state of liver, gills and brain of Cyprinus carpio. This was measured through the following biomarkers: hydroperoxide and protein carbonyl content, lipid peroxidation degree, as well as superoxide dismutase, catalase and glutathione peroxidase activity. Carbamazepine concentration in carp's tissue was also determined by liquid chromatography with a diode arrangement detector.