Cytotoxicity and Cell Death Induction on a Cervical Cancer Cell Line by Crude Extracellular Product of Omphalotus nidiformis (Agaricomycetes) Mycelium.

Fungi have proved to be useful sources of compounds with antineoplastic properties. Although several metabolites isolated from species of the genus Omphalotus have shown cytotoxic effects on tumor cell lines. Few works have studied Omphalotus nidiformis.

Effects of Mexican Ganoderma lucidum extracts on liver, kidney, and the gut microbiota of Wistar rats: A repeated dose oral toxicity study.

Well-characterized and standardized extracts of a Mexican genotype of Ganoderma lucidum (Gl), a medicinal mushroom, cultivated on oak sawdust (Gl-1) or oak sawdust plus acetylsalicylic acid (Gl-2, ASA), have been shown to exert antioxidant, hypocholesterolemic, anti-inflammatory, prebiotic, and anticancer properties. However, toxicity analyses still need to be carried out. Different doses of these Gl-1 or Gl-2 extracts were administered to Wistar rats for 14 days in a repeated dose oral toxicity study.