Publications by authors named "Isaac S Leichter"
We aimed to determine whether 80 kVp conventional nonenhanced head CT scans have better gray-white matter contrast than standard 120 kVp scans performed on the same patients. Thirty head CT scans acquired at 80 kVp (CT dose index [CTDI]vol 46) were compared to prior studies in the same patients performed at 120 kVp (CTDIvol 59). Signal (Hounsfield units [HU]), noise (sd HU), and contrast-to-noise ratio per dose (CNRD) were assessed in multiple cerebral gray and white matter regions of interest.
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- The study aimed to evaluate a computer-aided classification (CAC) system for identifying lesions in the BI-RADS category 3 based on mammogram images.
- The CAC system analyzed 106 lesions, utilizing quantitative features from digitized mammograms to determine malignancy likelihood; results showed high sensitivity (94%) and decent specificity (78%), indicating effective classification.
- Ultimately, the CAC system successfully upgraded the classification of 90% of malignant lesions initially categorized as probably benign, showing potential for improving diagnostic accuracy in breast cancer detection.
Rationale And Objectives: The purpose of this study was to determine whether the size of mammographically detected microcalcifications is predictive of malignancy.
Materials And Methods: Two hundred sixty mammograms showing clustered microcalcifications with proven diagnoses (160 malignant, 100 benign) were respectively reviewed by experienced mammographers. Lesions that were obviously benign in appearance were excluded from the study.