Publications by authors named "Isaac N Mueka"

Article Synopsis
  • Acute hyperglycemia is commonly observed in patients with acute coronary syndrome (ACS) and is linked to increased short- and long-term mortality.
  • A review of 1056 articles led to the inclusion of 21 studies, focusing on various measures of acute hyperglycemia and their effects on patient outcomes.
  • The findings suggest that stress hyperglycemia ratio (SHR), admission blood glucose (ABG), and fasting plasma glucose (FPG) are correlated with mortality in ACS patients, though further research is needed to refine the definition and cutoff levels for acute hyperglycemia.
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Genetic variations among people mainly determine the blood levels of lipoprotein (a) (Lp(a)), and it is relatively stable throughout one's lifetime. Nevertheless, there could still be other factors that control the Lp(a) level. Thyroid hormones are known to influence the serum lipid level by regulating the expression of key enzymes that are involved in lipid metabolism.

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Hypothyroidism, also known as underactive thyroid, is a condition where the thyroid gland does not produce enough thyroid hormone. Deficiency or lack of thyroid hormone causes patients to have a slower metabolism, which may lead to secondary medical issues such as weight gain, fatigue, depression, and increased cardiovascular risk. This systematic review aims to explore the effect of levothyroxine therapy on the lipid profile of hypothyroid patients.

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