Publications by authors named "Isaac Goldenthal"

Article Synopsis
  • - The study evaluated the AF-HEART intervention, which uses mobile and telehealth technologies, to enhance patient management of atrial fibrillation (AF) through remote tracking and professional guidance on lifestyle factors.
  • - Over 6 months, 20 patients demonstrated significant outcomes, including a median of 181 heart rhythm recordings, an average weight loss of 3.5 kilograms, and improved quality-of-life scores.
  • - The findings suggest the AF-HEART intervention is feasible for continuous monitoring and improving patient outcomes, indicating potential for a larger randomized trial.
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Article Synopsis
  • The study investigates how digital health tools, specifically the Alivecor® KardiaMobile ECG monitor, can help patients with atrial fibrillation (AF) self-manage their condition and identifies factors that encourage continuous usage.
  • Researchers analyzed data from 105 adults with AF to determine how often they used the monitor, categorizing usage into infrequent, moderate, and frequent.
  • Findings showed that frequent use was linked to experiencing premature atrial contractions (PACs), a lower symptom burden, and fewer concerns about treatment, suggesting these factors should be considered in future digital health research for AF management.
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  • A study analyzed intracardiac electrograms (EGMs) in 54 patients with atrial fibrillation (AF) to see how factors like BMI, age, and left atrial (LA) size affect EGM morphology.
  • The results indicated that higher BMI was linked to increased dominant frequency (DF) and mean spectral profile (MP), while older age and larger LA size were associated with decreased mean amplitude and width of the EGM.
  • These findings highlight how atrial remodeling due to these risk factors can lead to alterations in atrial activation patterns, potentially impacting the management and treatment of AF.
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  • Patients with atrial fibrillation (AF) often experience high levels of depressive symptoms (17.2%) and anxiety, which can impact the success of treatments like cardioversion and ablation.
  • The study assesses how these mental health issues affect quality of life during the procedures and whether they have any relation to AF recurrence within six months.
  • Results indicate that symptoms of depression and anxiety are prevalent among AF patients, and suggest that healthcare providers should routinely check for these issues and offer appropriate support during treatment.
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  • * The ACTION study aimed to evaluate the feasibility of a mobile health intervention to enhance cardiac health management through nurse-led support, encouraging patients to set and track personal cardiac health goals.
  • * In a six-month pilot with 53 participants, mostly overweight and with common health issues, the program was well-received, with nearly all (98%) appreciating regular support from a dedicated nurse through an online platform.
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Article Synopsis
  • * Recommendations include practical steps for managing procedures and care while minimizing exposure risk and optimizing resource use.
  • * Insights from four EP sections in a major New York City hospital highlight the importance of collaboration and adaptability in overcoming staffing and workflow challenges during the pandemic.
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Background: Clinically evident cardiac involvement has been documented in 5% of sarcoidosis patients, primarily manifesting as heart block, ventricular arrhythmias, and heart failure. Heart Rhythm Society consensus guidelines recommend advanced cardiac imaging with fluorodeoxyglucose-positron emission tomography (FDG-PET) scan for diagnosis of cardiac sarcoidosis, given endomyocardial biopsy's low sensitivity.

Case Summary: We describe four patients with cardiac sarcoidosis diagnosed with FDG-PET scan performed using a standardized imaging protocol for cardiac sarcoidosis.

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Article Synopsis
  • Atrial fibrillation (AF) is linked to high recurrence rates and poor health-related quality of life (HRQOL), and there are limited interventions currently available to help improve HRQOL for patients.
  • This study tested the iHEART intervention, which includes smartphone ECG monitoring and motivational texts, against usual care for patients with AF over 6 months to see its effect on HRQOL.
  • Results showed both groups experienced improvements in AF-specific HRQOL, but there were no significant differences between the two groups; further research is recommended to explore long-term impacts and accommodate various AF patient needs.
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  • * Out of 195 analyzed LVAD patients, 47% experienced significant VAs prior to the device implant, with 41% showing recurrent VAs post-implant during an average follow-up of 17 months.
  • * The presence of pre-LVAD AF significantly increased the risk of recurrent VAs (hazard ratio of 3.73), which were also linked to a higher mortality rate (hazard ratio of
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  • The study assessed how daily ECG self-recordings affect the detection and treatment timing of recurrent atrial fibrillation (AF) or atrial flutter (AFL) in patients undergoing specific treatments.
  • A total of 238 patients were divided into a control group receiving standard care and an intervention group using a mobile ECG device, revealing that the intervention group had a higher likelihood of detecting recurrence.
  • Results indicate that while mobile ECG devices facilitate earlier detection of AF/AFL recurrences, they also showed that control patients had a shorter time from detection to treatment.
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