Publications by authors named "Isaac Chukwunwike Abanum"
Basic Clin Neurosci
January 2023
Article Synopsis
- Researchers investigated the neuroprotective effects of a low dose of datumetine on mice, noting its previous link to NMDAR signaling and glutamate toxicity.
- The study involved 30 male BALB/c mice, divided into three groups, receiving different injections to evaluate the impact of datumetine and MK-801 on various brain regions.
- Results showed datumetine downregulated certain proteins in the hippocampus and prefrontal cortex, while some effects were reversed by MK-801, with no significant histological changes found in the brain tissue.*
