What is the role of brown adipose tissue in metabolic health: lessons learned and future perspectives in the long COVID?

Metabolic physiology plays a key role in maintaining our health and resilience. Metabolic disorders can lead to serious illnesses, including obesity. The pathogenesis of the new long COVID syndrome in individuals with long-term recovery after SARS-Co-2 infection is still incomplete.

Long COVID prevalence and physiology-centered risks: population-based study in Ukraine.

Aim: Multifaceted long COVID caused by SARS-COV-2 affects all populations in the World and takes priority over any other research topics for health care. The purpose of study is to identify physiology-centered risks, prevalence, symptoms and laboratory findings in patients with long COVID in Ukraine.

Methods: A prospective, cohort study was carried out on 332 patients with long COVID after 4 weeks and more after acute infection COVID-19 from Jul 1, 2021, to Jul 1, 2022.

What is the role of brown adipose tissue in metabolic health: lessons learned and future perspectives in the long COVID?

Metabolic physiology plays a key role in maintaining our health and resilience. Metabolic disorders can lead to serious illnesses, including obesity. The pathogenesis of the new long COVID syndrome in individuals with long-term recovery after SARS-Co-2 infection is still incomplete.

Roberts Bartholow: the progenitor of human cortical stimulation and his contentious experiment.

Roberts Bartholow, a physician, born and raised in Maryland, was a surgeon and Professor in Medicine who had previously served the Union during the Civil War. His interest in scientific research drove him to perform the first experiment that tested the excitability of the human brain cortex. His historical experiment on one of his patients, Mary Rafferty, with a cancerous ulcer on the skull, was one of his great accomplishments.

Somatosensory evoked potentials.

Somatosensory evoked potentials (SEPs) have been routinely used over the years to evaluate the somatosensory pathway and thereby supplement the diagnostic process when the history, neurologic examination, and imaging were not fully conclusive. The utilization of SEPs has become more popular in recent years despite the advance of imaging studies such as magnetic resonance imaging (MRI). Although no agreement has been found on the nomenclature and origins of some of the potentials, the most consistently recognized potentials have been used in clinical practice with montages and normative values set by each individual laboratory.

Factors that modify the risk of intraoperative seizures triggered by electrical stimulation during supratentorial functional mapping.

Objective: Intraoperative mapping via electrical stimulation is the gold standard technique for surgeries close to the eloquent cortex. However, it can trigger seizures which immediately impact patient's safety. We studied whether administration of antiepileptic drugs (AED) prior to and/or at the beginning of the surgery decreases the probability of triggering seizures, while adjusting for other risk factors.

Electrophysiology of Cranial Nerve Testing: Trigeminal and Facial Nerves.

The clinical examination of the trigeminal and facial nerves provides significant diagnostic value, especially in the localization of lesions in disorders affecting the central and/or peripheral nervous system. The electrodiagnostic evaluation of these nerves and their pathways adds further accuracy and reliability to the diagnostic investigation and the localization process, especially when different testing methods are combined based on the clinical presentation and the electrophysiological findings. The diagnostic uniqueness of the trigeminal and facial nerves is their connectivity and their coparticipation in reflexes commonly used in clinical practice, namely the blink and corneal reflexes.

Leg amyotrophic diplegia: prevalence and pattern of weakness at US neuromuscular centers.

Objective: To identify the frequency of leg amyotrophic diplegia (LAD) at a US academic center, describe the pattern of weakness, and provide comparative data from 8 additional major US academic institutions.

Background: LAD is a leg onset variant of progressive muscular atrophy (PMA). LAD weakness is confined to the legs for at least 2 years, and there are no upper motor neuron signs.