Heart reaction of male and female with streptozotocin induced diabetes on cholinergic impacts.

Objective: The aim: Find out the nature of the changes sensitivity of the heart to the cholinergic influences the development of diabetes depending on gender.

Patients And Methods: Materials and methods: In experiments on adult male and female rats, type 1 diabetes by momentary introduction of streptozotocin at a dose of 60 mg/ kg into the peritoneal cavity was modeled. Animals were examined after 15, 30, 60 and 90 days after introduction of streptozotocin.