Preparation and characterization of single perovskite microplates and its sunlight assisted photodecolorization activity, validated by response surface methodology.

Perovskites overtaking simple metal oxides as solar light harvesting material due to their excellent photocatalytic efficiency and superior stability. An efficient visible light responsive, KBaCuO single perovskites oxides (SPOs) photocatalyst was fabricated by a facile hydrothermal method. The fabricated SPOs was characterized by various techniques.

Protects Rats against CCl-Induced Hepatic Injuries through Modulation of an Unfolded Protein Response Pathway and Pro-Inflammatory Intermediates.

Liver fibrosis is a major pathological feature of chronic liver disease and effective therapies are limited at present. The present study focuses on the hepatoprotective potential of . against carbon tetrachloride (CCl)-induced liver damage in rats.

Comparative robustness and sustainability of in-situ prepared antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan in environmental remediation perspective.

Due to the rapid race of industrialization natural assets like fresh water has been deteriorated causing lethal effects in living organisms. In the current study robust and sustainable composite of in-situ antimony nanoarchitectonics in chitosan/synthesized carboxymethyl chitosan matrix were synthesized. To improve solubility, metal adsorption and water decontamination, chitosan was modified into carboxymethyl chitosan and the modification was confirmed through various characterization techniques.

Joubert syndrome a rare entity and role of radiology: A case report.

Introduction And Importance: Joubert syndrome (JS) is defined by the characteristic set of cerebellum and midbrain abnormalities that communally result in the indicative "molar tooth sign" on the axial MRI report. The incidence of estimated to be from 1:80,000 to 1:100,000.

Case Presentation: Clinical features can be noticed shortly after birth that includes hypotonia episodic tachypnea and apnea that may be followed by developmental delays and speech apraxia.

The status of knowledge, attitude and practice towards emergency management of avulsed tooth among dental students: A single center cross-sectional study.

Objective: To evaluate the awareness of emergency trauma management and the potential role of dentists in handling tooth avulsion injuries.

Methods: The cross-sectional study was conducted at the Dental Outpatients Department of Jinnah Medical and Dental College, Karachi, from December 2020 to March 2021, and comprised dentists and final year dental students of either gender. Data was collected using a 17-item questionnaire to assess the awareness level regarding the knowledge of traumatic dental emergencies and the role of a dentist in handling a traumatic tooth injury.

The multifaceted antineoplastic role of pyrimethamine against human malignancies.

Cancer accounted for nearly 10 million deaths in 2020 and is the second leading cause of death worldwide. The chemotherapeutic agents that are in clinical practice possess a broad range of severe adverse effects towards vital organs which emphasizes the importance of the discovery of new therapeutic agents or repurposing of existing drugs for the treatment of human cancers. Pyrimethamine is an antiparasitic drug used for the treatment of malaria and toxoplasmosis with a well-documented excellent safety profile.

Indigofera linifolia ameliorated CCl induced endoplasmic reticulum stress in liver of rat.

Ethnopharmacological Relevance: Indigofera linifolia (L.f.) Retz.

Pilea umbrosa ameliorate CCl induced hepatic injuries by regulating endoplasmic reticulum stress, pro-inflammatory and fibrosis genes in rat.

Background: Pilea umbrosa (Urticaceae) is used by local communities (district Abbotabad) for liver disorders, as anticancer, in rheumatism and in skin disorders.

Methods: Methanol extract of P. umbrosa (PUM) was investigated for the presence of polyphenolic constituents by HPLC-DAD analysis.

An Overview of the Potential Antineoplastic Effects of Casticin.

Cancer persists as one of the leading causes of deaths worldwide, contributing to approximately 9.6 million deaths per annum in recent years. Despite the numerous advancements in cancer treatment, there is still abundant scope to mitigate recurrence, adverse side effects and toxicities caused by existing pharmaceutical drugs.

Anticancer Potential of Raddeanin A, a Natural Triterpenoid Isolated from .

Natural compounds extracted from plants have gained immense importance in the fight against cancer cells due to their lesser toxicity and potential therapeutic effects. Raddeanin A (RA), an oleanane type triterpenoid is a major compound isolated from . As an anticancer agent, RA induces apoptosis, cell cycle arrest, inhibits invasion, migration and angiogenesis in malignant cell lines as well as in preclinical models.

An overview of the potential anticancer properties of cardamonin.

Cancer is one of the leading causes of mortality, contributing to 9.6 million deaths globally in 2018 alone. Although several cancer treatments exist, they are often associated with severe side effects and high toxicities, leaving room for significant advancements to be made in the field.

An overview of the anti-cancer actions of Tanshinones, derived from (Danshen).

Tanshinone is a herbal medicinal compound described in Chinese medicine, extracted from the roots of (Danshen). This family of compounds, including Tanshinone IIA and Tanshinone I, have shown remarkable potential as anti-cancer molecules, especially against breast, cervical, colorectal, gastric, lung, and prostate cancer cell lines, as well as leukaemia, melanoma, and hepatocellular carcinoma among others. Recent data has indicated that Tanshinones can modulate multiple molecular pathways such as PI3K/Akt, MAPK and JAK/STAT3, and exert their pharmacological effects against different malignancies.

Methanol extract of ameliorates CCl induced hepatic injuries by regulation of genes in rats.

We have investigated the protective potential of methanol extract of (IAM) on the expression of endoplasmic reticulum (ER) stress associated genes and inflammatory genes on carbon tetrachloride (CCl) induced hepatic toxicity in rats. Hepatic damage markers: aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and bilirubin were elevated while the content of antioxidants: catalase (CAT), superoxide dismutase (SOD), peroxidase (POD) and reduced glutathione (GSH) were decreased significantly ( < 0.05) in CCl treated rats as compared to the control group.

Brachychiton populneus (Schott & Endl.) R.Br. ameliorate carbon tetrachloride induced oxidative stress through regulation of endoplasmic reticulum stress markers and inflammatory mediators in Sprague-Dawley male rats.

In this study hepatoprotective aptitude of Brachychiton populneus against carbon tetrachloride (CCl) instigated liver injuries in rats was investigated. High-performance liquid chromatography (HPLC) with a diode array detector (DAD) analysis of methanol extract of B. populneus (BPM) indicated existence of rutin, catechin and myricetin.

Alleviation of heavy metals toxicity by the application of plant growth promoting rhizobacteria and effects on wheat grown in saline sodic field.

The aim of the study was to determine tolerance of plant growth promoting rhizobacteria (PGPR) in different concentrations of Cu, Cr, Co, Cd, Ni, Mn, and Pb and to evaluate the PGPR-modulated bioavailability of different heavy metals in the rhizosphere soil and wheat tissues, grown in saline sodic soil. Bacillus cereus and Pseudomonas moraviensis were isolated from Cenchrus ciliaris L. growing in the Khewra salt range.

Diagnostic accuracy, sensitivity, specificity and positive predictive value of fine needle aspiration cytology (FNAC) in intra oral tumors.

Objective: The objective of this study was to establish the diagnostic accuracy, specificity and sensitivity of fine needle aspiration cytology(FNAC) for intra-oral tumors, comparing with histopathology as the gold standard.

Materials And Methods: Forty cases of FNA cytology from intraoral tumors was performed in AFID along with the demographic data and clinical information and then diagnosed at AFIP, Rawalpindi. Then the cytology results obtained per FNAC were compared with the histopathological biopsy results of the same lesions.

Frequency and clinical importance of anti-Tg auto-antibodies (ATG).

Objective: To note the frequency of anti thyroglobulin autoantibodies (ATG) and its clinical importance in 25 follow-up cases of differentiated thyroid cancer (DTC).

Design: A case control study.

Place And Duration Of Study: The total duration of study was one year (September 2000 to August 2001).