Publications by authors named "Irtiqa Fazili"
Article Synopsis
- Patients with cystic fibrosis (CF) often use many antibiotics and have an altered gut microbiome, which increases the risk of Clostridioides difficile infections (CDI), though symptomatic CDI is rare in adults with CF.
- A study found that 32% of children with CF are colonized by C. difficile without exhibiting gastrointestinal symptoms, raising questions about the reasons behind this occurrence.
- Factors like a higher body mass index (BMI) and prior exposure to certain antibiotics were linked to this asymptomatic colonization, but none of the children showed symptoms of CDI within 90 days after the study started.
Background: Esophageal conditions result in significant morbidity and mortality worldwide. There is growing enthusiasm for discerning the role of microbiome in esophageal diseases. Conceivably, the focus has been on examining the role of local microbiome in esophageal diseases although this is somewhat limited by the invasive approach required to sample the esophageal tissue.
View Article and Find Full Text PDFObjectives: Recent Infectious Disease Society of America guidelines recommend multistep testing algorithms to diagnose Clostridioides difficile infection (CDI), including a combination of nucleic acid amplification-based testing (NAAT) and toxin enzyme immunoassay (EIA). The use of these algorithms in children, including the ability to differentiate between C. difficile colonization and CDI, however, has not been evaluated.
View Article and Find Full Text PDFBackground: Medical school wellness programs are rapidly becoming a prevalent feature of medical education. The wellness component of medical education is addressed by a multitude of different approaches, but is often led by administrative faculty rather than students.
Approach: The first-year medical student authors collectively established a medical school wellness committee that is entirely student-driven.