Publications by authors named "Irna Carneiro"
Carbapenem-resistant Klebsiella pneumoniae is a common cause of healthcare-related infections, and it is widespread in hospitals and diverse environments with potentially serious public health implications. Herein, we have reported the isolation and characterization of an environmental Brazilian Klebsiella carbapenemase (BKC-1)-producing K. pneumoniae strain (IEC1205) isolated in 2018 from a river in the Amazon region, Brazil.
View Article and Find Full Text PDFPseudomonas aeruginosa is the leading cause of nosocomial infections with high mortality rates owing to the limited therapeutic options for multidrug-resistant Pseudomonas aeruginosa (MDRPA) and metallo-beta-lactamase (MBL)-producing strains. Herein, we present a meta-analysis exploring the association between MDRPA and São Paulo MBL-1 (SPM-1)-producing strains vs. mortality.
View Article and Find Full Text PDFBackground: Healthcare-associated infections (HCAIs) challenge public health in developing countries such as Brazil, which harbour social inequalities and variations in the complexity of healthcare and regional development.
Aim: To describe the prevalence of HCAIs in hospitals in a sample of hospitals in Brazil.
Methods: A prevalence survey conducted in 2011-13 enrolled 152 hospitals from the five macro-regions in Brazil.
Objective: to define the profile and analyze the postoperative evolution of children with parapneumonic pleural effusion (PPE), and to evaluate strategies used in the presence of diagnostic and therapeutic limitations, emphasizing the open thoracic drainage (OTD) .
Methods: we conducted a cross-sectional, prospective, analytical study in which we followed children admitted in an Amazon university hospital with surgically addressed PPE, from October 2010 to October 2011.
Results: we studied 46 patients, most children under three years of age (74%), with no gender predominance.
Clinical and microbiological features of infections caused by Pseudomonas aeruginosa in patients hospitalized in intensive care units.
Rev Soc Bras Med Trop
March 2017
Introduction: The spread of multidrug-resistant Pseudomonas aeruginosa in Brazilian hospitals has greatly impacted upon the morbidity and mortality of individuals in intensive care units. Given the lack of information regarding the dynamics of multidrug resistance in northern Brazil, we analyzed the clinical and microbiological features of nosocomial infections caused by P. aeruginosa.
View Article and Find Full Text PDFBackground: Minimal structure is required for effective prevention of health care-associated infection (HAI). The objective of this study was to evaluate the structure for prevention of HAI in a sample of Brazilian hospitals.
Methods: This was a cross-sectional study from hospitals in 5 Brazilian regions (n = 153; total beds: 13,983) classified according to the number of beds; 11 university hospitals were used as reference for comparison.
We evaluated the epidemiology of Acinetobacter spp. recovered from patients diagnosed with bloodstream infections in 9 tertiary hospitals located in all Brazilian geographic regions between April and August 2014. Although OXA-23-producing Acinetobacter baumannii clones were disseminated in most hospitals, it was observed for the first time the spread of OXA-72 among clonally related A.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated nosocomial bloodstream infections (nBSIs) in pediatric patients in Brazil from June 2007 to March 2010, identifying common pathogens and their resistance to antibiotics.
- - Out of 2,563 reported cases, 342 significant nBSI episodes were found, primarily caused by Gram-negative bacteria (49%) and Gram-positive bacteria (42.6%), with a notable 21.6% mortality rate among affected patients.
- - Central venous catheters were major predisposing factors for these infections, and a concerning number of pathogens, including S. aureus and Klebsiella spp., exhibited high levels of antibiotic resistance.
Nosocomial bloodstream infections (nBSIs) are an important cause of morbidity and mortality. Data from a nationwide, concurrent surveillance study, Brazilian SCOPE (Surveillance and Control of Pathogens of Epidemiological Importance), were used to examine the epidemiology and microbiology of nBSIs at 16 Brazilian hospitals. In our study 2,563 patients with nBSIs were included from 12 June 2007 to 31 March 2010.
View Article and Find Full Text PDFIntroduction: The outbreak occurred between February and June 2006 and included identification of the cases, analysis of medical records, cultures from environmental sources, resistance analyses and genotyping profile of Serratia marcescens.
Methods: The cultures were composed of 13 blood isolates, 17 rectal and hand swabs and air sampling.
Results: The data obtained by pulsed-field gel electrophoresis exhibited three strains that contaminated 24 patients.