Addition of 2.5 g L-arginine in a fatty meal prevents the lipemia-induced endothelial dysfunction in healthy volunteers.

Background: Endothelial function as determined by flow-mediated dilation (FMD) deteriorates during postprandial lipemia. The impairment can be neutralized by adding 50 g casein to the fatty meal. The objective of this study was to see which of the casein constituents is responsible for this neutralization effect.