Publications by authors named "Irma van den Hengel-Koot"
Article Synopsis
- The INTOXICATE study created the first multicenter database on poisoned patients in ICUs, aiming to assess the rate of patients requiring significant interventions upon admission.
- Conducted across 78 ICUs from Europe, Australia, and the Eastern Mediterranean, the study involved 2,273 adults, with 68% experiencing what was classified as an 'eventful admission' due to severe intoxication.
- Findings revealed that while 95.5% of patients survived their ICU stay, about one-third did not receive major interventions, shedding light on the treatment patterns for acute poisoning cases in intensive care.
Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020.
Clin Toxicol (Phila)
June 2024
Article Synopsis
- This study evaluates the clinical features and outcomes of acute cannabis toxicity versus acute synthetic cannabinoid receptor agonist toxicity in European emergency departments from 2013-2020.
- Using data from the European Drug Emergencies Network Plus, researchers analyzed 2,657 cases of cannabis exposure and 503 cases of synthetic cannabinoid exposure to compare their effects.
- The findings indicate that synthetic cannabinoid exposures are linked to more severe neuropsychiatric symptoms, while cannabis exposures are associated with cardiovascular issues.
Introduction: The number of patients with excessive nitrous oxide (N2O) use and neurological disorders has been rising, indicating an addictive potential of N2O. We studied the incidence of self-reported substance use disorder (SUD)-related symptoms, signs of neuropathy, and the patterns of use in N2O-intoxicated patients.
Methods: The Dutch Poisons Information Center (DPIC) provides information by telephone on the management of intoxications to healthcare professionals.
Background: Poisoned patients are frequently admitted following Emergency Department (ED) presentation, while the necessity of such admissions is hardly investigated. We determined the proportion and characteristics of poisoned patients who were admitted, but in retrospect had an uneventful admission.
Methods: For this observational cohort study, all patients presented to the ED of a Dutch University Hospital with various poisonings during a 1.