Publications by authors named "Irit Itzhaki Van-Ham"
Page 1 of 1
Synopsis of recent research by authors named "Irit Itzhaki Van-Ham"
- Irit Itzhaki Van-Ham's research primarily investigates the differential signaling and regulation of dopamine D2 receptor isoforms (D2S and D2L), highlighting their roles in neuropharmacology and potential implications for conditions such as addiction and schizophrenia.
- Recent findings indicate that the phosphorylation sites on the dopamine D2S receptor are critical for its desensitization by protein kinase C, marking significant differences in the desensitization mechanisms of the two receptor isoforms.
- In addition to dopamine receptors, her work includes exploring G-protein coupled receptors (GPCRs) and their rapid desensitization mechanisms in Xenopus oocytes, revealing the involvement of Go G-proteins and providing insights into receptor regulation dynamics.
