Publications by authors named "Iris E Derwig"

Although many pregnant women have been infected by coronavirus, the presence of intrauterine vertical transmission has not been conclusively reported yet. What prevents this highly contagious virus from reaching the fetus? Is it only the presence of a strong placental barrier, or is it the natural absence of the some receptor that the viruses use for transmission? We, therefore, need to comprehensively understand the mechanism of action of the mammalian epithelial barriers located in two different organs with functional similarity. The barriers selected as potential targets by SARS-CoV-2 are the alveolo-capillary barrier (ACB), and the syncytio-capillary barrier (SCB).

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Article Synopsis
  • The study examines the link between placental volume in the second trimester, uterine artery blood flow, and neonatal birth weight in 83 singleton pregnancies.
  • Results show that normal pregnancies had increasing placental volumes with gestational age, whereas those leading to small for gestational age (SGA) neonates exhibited significantly smaller placental volumes and higher uterine artery resistance.
  • Findings suggest that a smaller placental volume during the second trimester is associated with increased risks of SGA births and can be indicative of placental blood flow issues.
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