Publications by authors named "Irina V Gladysheva"
Intermicrobial interactions play a key role in the regulation of microbial populations and the colonization of various ecological niches. In the present study, we assessed the effect of cell-free supernatants (CFSs) from the vaginal isolates Corynebacterium amycolatum ICIS 53 and Corynebacterium amycolatum ICIS 82 on urogenital test strain biofilm formation of Staphylococcus aureus. Our studies showed that the CFSs of both C.
View Article and Find Full Text PDFBiofilm formation is an important factor in the development of antibiotic resistance and chronic infection. In this study, we demonstrated that the cell-free supernatant of vaginal isolates of C. amycolatum caused a reduction in biofilm formation, destroyed the preformed biofilms, altered the cell surface properties and reduced the production of exopolysaccharides in clinical isolates of P.
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- Corynebacterium amycolatum ICIS 99, isolated from healthy women's vaginal smears, demonstrated positive antimicrobial potential, prompting a genome analysis.
- The draft genome is 2,532,503 bp long, containing 2186 coding sequences with a G + C content of 59.0%, and lacks true virulence factors.
- It has genes that help it survive in the vaginal environment and produce beneficial metabolites, suggesting its potential as a safe probiotic strain; the genomic data is available in major databases.
Article Synopsis
- * Genome sequencing of three vaginal strains revealed their ability to produce metabolites that enhance the fighting power of beneficial bacteria against harmful microorganisms.
- * These strains show genes that help them survive in the vaginal environment and have potential as probiotics to prevent pathogenic growth and support healthy colonization.
ICIS 9 was isolated from a vaginal smear of a healthy woman. Here, we report the draft genome sequence of ICIS 9, which will be useful for further studies of specific genetic features of this strain and for understanding its probiotic properties.
View Article and Find Full Text PDFThis report describes the draft genome sequence of Corynebacterium amycolatum strain ICIS 53, isolated from the reproductive tract of a healthy woman. The size of the genome was 2,460,257 bp (58.98% G+C content).
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