Publications by authors named "Irina Remsburg"
Purpose: To assess the potential of whole-genome sequencing (WGS) to replicate and augment results from conventional blood-based newborn screening (NBS).
Methods: Research-generated WGS data from an ancestrally diverse cohort of 1,696 infants and both parents of each infant were analyzed for variants in 163 genes involved in disorders included or under discussion for inclusion in US NBS programs. WGS results were compared with results from state NBS and related follow-up testing.
Article Synopsis
- Late preterm births (35-36 weeks) may lead to lower intellectual and behavioral outcomes in early childhood compared to full-term births (37-41 weeks), influencing development significantly.
- A study involving 278 late preterm and 192 term children found that late preterm children had lower scores in various cognitive and adaptability measures, with gestational age being a key predictor of these outcomes.
- The findings suggest that interrupting the natural course of gestation can have subtle but important long-term developmental consequences, urging caution in decisions about early elective deliveries.