Publications by authors named "Irina Petcu"
Accumulating data suggest that chronic neuroinflammation-mediated neurodegeneration is a significant contributing factor for progressive neuronal and glial cell death in age-related neurodegenerative pathology. Furthermore, it could be encountered as long-term consequences in some viral infections, including post-COVID-19 Parkinsonism-related chronic sequelae. The current systematic review is focused on a recent question aroused during the pandemic's successive waves: are there post-SARS-CoV-2 immune-mediated reactions responsible for promoting neurodegeneration? Does the host's dysregulated immune counter-offensive contribute to the pathogenesis of neurodegenerative diseases, emerging as Parkinson's disease, in a complex interrelation between genetic and epigenetic risk factors? A synthetic and systematic literature review was accomplished based on the "Preferred Reporting Items for Systematic Principles Reviews and Meta-Analyses" (PRISMA) methodology, including registration on the specific online platform: International prospective register of systematic reviews-PROSPERO, no.
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- Certain bacteria can be harmful, so animals need to balance the nutritional benefits of food against possible negative effects after eating.
- In a study with Drosophila (fruit flies), researchers found that flies initially preferred the scent of harmful bacteria but eventually learned to avoid them after a negative experience.
- This learning process involves the immune system communicating with the brain, particularly through the mushroom body, which is crucial for memory, and relies on specific immune receptors in the brain's octopaminergic neurons.