Publications by authors named "Irina Grigor'eva"
The last decade saw extensive studies of the human gut microbiome and its relationship to specific diseases, including gallstone disease (GSD). The information about the gut microbiome in GSD-afflicted Russian patients is scarce, despite the increasing GSD incidence worldwide. Although the gut microbiota was described in some GSD cohorts, little is known regarding the gut microbiome before and after cholecystectomy (CCE).
View Article and Find Full Text PDFObesity is a major risk factor for developing gallstone disease (GSD). Previous studies have shown that obesity is associated with an elevated ratio in the gut microbiota. These findings suggest that the development of GSD may be related to gut dysbiosis.
View Article and Find Full Text PDFArticle Synopsis
- Gallstone disease (GSD) is a significant public health issue linked to high costs and complications, with increasing evidence connecting the disease to the gut microbiota.
- Studies show that bacteria in the mouth and gastrointestinal tract influence gallbladder motility and mucin gene expression, potentially promoting gallstone formation.
- The impact of gallbladder removal on microbiota composition raises concerns about increased cancer risks, highlighting the need for further research on microbiota evaluation as a diagnostic tool for gastroenterological diseases.