Publications by authors named "Irina Gasslitter"
Article Synopsis
- Pneumonia, caused by viruses and bacteria, triggers both innate and adaptive immune responses, which can be measured through biomarkers like C-reactive protein (CRP) and Neopterin.
- A study involving 194 patients aimed to evaluate these biomarkers in differentiating between viral and bacterial pneumonia and to assess the occurrence of neuropsychiatric symptoms among patients.
- Results indicated that higher CRP/Neopterin ratios are linked to bacterial pneumonia, while lower ratios were found in COVID-19 and bacterial superinfections, successfully distinguishing between the types of pneumonia and indicating the presence of superinfections.
Article Synopsis
- Serovar L1-L3 of Chlamydia trachomatis causes lymphogranuloma venereum (LGV), with rising cases among HIV-positive men who have sex with men (MSM), making differentiation between LGV and other CT infections crucial for treatment.
- A study analyzed 2,083 CT infections from 1,479 patients in Austria between 2014 and 2021, revealing that LGV was found in 15% of cases and accounted for 23% of rectal CT infections in MSM.
- Most LGV cases were among MSM, often HIV-positive, and frequently included concurrent syphilis; interestingly, 45% of LGV cases were asymptomatic, indicating the need
Article Synopsis
- - The incidence of pyogenic spondylodiscitis is rising in Europe and North America, possibly due to more people with risk factors, but it's unclear how much HIV, even with effective ART, contributes to this risk.
- - The study presents seven cases of pyogenic spondylodiscitis in six HIV patients on ART, all showing severe pain and high inflammatory markers; diagnosis was confirmed through MRI and pathogen isolation.
- - Surgical intervention was necessary for all patients, with an average antibiotic treatment lasting about 17 weeks; five patients fully recovered while one patient died from multi-organ failure, highlighting the growing risk for spondylodiscitis in older HIV patients with comorbidities.
Hidradenitis suppurativa is a chronic, recurrent, autoinflammatory skin disease of the hair follicle and sebaceous glands in intertriginous skin areas. Treatment is based on clinical severity (typically classified according to Hurley stage). In advanced stages, radical excision of affected skin areas with secondary wound closure remains first-line treatment.
View Article and Find Full Text PDFHintergrund: Ichthyosen sind eine heterogene Gruppe von Krankheiten, deren klinische Klassifizierung schwierig ist. Hier wird die Ichthyosekohorte eines Expertisezentrums für Genodermatosen im Detail beschrieben.
Patienten Und Methodik: Eingeschlossen wurden Patienten mit klinisch oder genetisch bestätigter Ichthyose, die zwischen 2004 und 2017 untersucht und in einer Datenbank aufgenommen wurden.
Background: Ichthyoses are a heterogeneous disease group, which makes clinical classification challenging. An ichthyosis cohort at a center for genodermatoses is presented in detail.
Patients And Methods: Patients with clinically and/or genetically confirmed ichthyosis seen from 2004 to 2017 and listed in a database were included.
IL-17 blockers are among the newer anti-psoriatic treatment options and little is known about the interclass switching. We have thus initiated a multi-center, multi-national, retrospective study to assess the treatment response of patients who were switched from one IL-17 blocker to another. Analysis consisted of data from patients with moderate-to-severe psoriasis who did not respond satisfactorily to one of the available IL-17 blockers (secukinumab, ixekizumab, brodalumab) and were subsequently switched to another drug of this class.
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