Publications by authors named "Irina G A Ruether"

Article Synopsis
  • * A study analyzed cervical samples to evaluate HPV16 DNA integration by measuring the ratios of E1/E6 and E2/E6, revealing significant findings in both low-grade and high-grade cervical lesions.
  • * The results suggest that these DNA ratio measurements can effectively indicate HPV16 integration patterns and may help in predicting cancer progression in cervical dysplasia cases.
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Enteroviruses, the main cause of aseptic meningitis, consist of 100 serotypes, and many of them have been associated with large outbreaks. In the present study, a comparison of RFLP analysis of the 5' untranslated region (5'UTR) and sequencing of both the 5'UTR and VP1 regions was conducted for epidemiological linkage of 27 clinical enterovirus strains. The clinical enterovirus strains were clustered into five restriction profile groups.

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Echovirus 6 (E6) is one of the main enteroviral serotypes that was isolated from cases of aseptic meningitis and encephalitis during the last years in Greece. Two E6 (LR51A5 and LR61G3) were isolated from the sewage treatment plant unit in Larissa, Greece, in May 2006, 1 year before their characterization from aseptic meningitis cases. The two isolates were initially found to be intra-serotypic recombinants in the genomic region VP1, a finding that initiated a full genome sequence analysis.

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