Publications by authors named "Irina Balygina"
Denham Harman's oxidative damage theory identifies superoxide (O) radicals as central agents of aging and radiation injury, with Mn-dependent superoxide dismutase (MnSOD) as the principal O-scavenger. However, in the radiation-resistant nematode Caenorhabditis elegans, the mitochondrial antioxidant enzyme MnSOD is dispensable for longevity, and in the model bacterium Deinococcus radiodurans, it is dispensable for radiation resistance. Many radiation-resistant organisms accumulate small-molecule Mn-antioxidant complexes well-known for their catalytic ability to scavenge O, along with MnSOD, as exemplified by D.
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- Chronic ionizing radiation from sources like nuclear accidents and space exploration threatens human health, but fungi show remarkable resistance to such radiation.
- A study tested 95 fungal isolates for their ability to withstand chronic ionizing radiation, heavy metals, high temperatures, and low pH, giving insights into their resistance mechanisms.
- Results indicated that resistance to chronic ionizing radiation in fungi is primarily linked to their resistance to chromium and elevated temperatures, highlighting fundamental differences in how fungi cope with chronic versus acute radiation exposure.