Publications by authors named "Iria Gomez-Diaz"
Article Synopsis
- * The study involved analyzing genetic data from over 7,400 people with DCM or LVNC and found that this variant is significantly more common in these patients compared to larger control groups, indicating a strong association.
- * Among individuals carrying this variant, nearly 72% exhibited DCM or LVNC, with a notable portion also having congenital heart defects; however, the overall disease progression was mild, with few experiencing severe complications over an extended follow-up period.
Objective: Up to 50% of patients with hypertrophic cardiomyopathy (HCM) show no disease-causing variants in genetic studies. has been suggested as a candidate gene for the development of cardiomyopathies, although evidence for a causative role in HCM is limited. We sought to investigate the relationship between rare variants in and the development of HCM.
View Article and Find Full Text PDFBackground: Dilated cardiomyopathy (DCM) is the most frequent cause of heart transplantation (HTx). The genetic basis of DCM among patients undergoing HTx has been poorly characterized. We sought to determine the genetic basis of familial DCM HTx and to establish the yield of modern next generation sequencing (NGS) technologies in this setting.
View Article and Find Full Text PDF