Publications by authors named "Irfat Jan"

We recently developed a database for hexaploid wheat QTL (WheatQTLdb; www.wheatqtldb.net), which included 11,552 QTL affecting various traits of economic importance.

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In wheat, multiple disease resistance meta-QTLs (MDR-MQTLs) and underlying candidate genes for the three rusts were identified which may prove useful for development of resistant cultivars. Rust diseases in wheat are a major threat to global food security. Therefore, development of multiple disease-resistant cultivars (resistant to all three rusts) is a major goal in all wheat breeding programs worldwide.

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Unlabelled: Majority of cereals are deficient in essential micronutrients including grain iron (GFe) and grain zinc (GZn), which are therefore the subject of research involving biofortification. In the present study, 11 meta-QTLs (MQTLs) including nine novel MQTLs for GFe and GZn contents were identified in wheat. Eight of these 11 MQTLs controlled both GFe and GZn.

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Article Synopsis
  • Wheat is a crucial cereal crop, but leaf rust diseases can significantly reduce yields, sometimes by over 50%.
  • This mini-review discusses various Lr genes, including alien sources and novel resistance genes, as well as recent findings on QTLs and MTAs related to leaf rust resistance since 2018.
  • It also covers the introgression of Lr genes into commercial cultivars from 18 countries and addresses challenges and future directions in breeding leaf rust-resistant wheat.
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In bread wheat, meta-QTL analysis was conducted using 353 QTLs that were available from earlier studies. When projected onto a dense consensus map comprising 76,753 markers, only 184 QTLs with the required information, could be utilized leading to identification of 61 MQTLs spread over 18 of the 21 chromosomes (barring 5D, 6D and 7D). The range for mean R (PVE %) was 1.

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During the last three decades, QTL analysis in wheat has been conducted for a variety of individual traits, so that thousands of QTL along with the linked markers, their genetic positions and contribution to phenotypic variation (PV) for concerned traits are now known. However, no exhaustive database for wheat QTL is currently available at a single platform. Therefore, the present database was prepared which is an exhaustive information resource for wheat QTL data from the published literature till May, 2020.

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SET domain genes (SDGs) that are involved in histone methylation have been examined in many plant species, but have never been examined in bread wheat; the histone methylation caused due to SDGs is associated with regulation of gene expression at the transcription level. We identified a total of 166 bread wheat TaSDGs, which carry some interesting features including the occurrence of tandem/interspersed duplications, SSRs (simple sequence repeats), transposable elements, lncRNAs and targets for miRNAs along their lengths and transcription factor binding sites (TFBS) in the promoter regions. Only 130 TaSDGs encoded proteins with complete SET domain, the remaining 36 proteins had truncated SET domain.

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Article Synopsis
  • A Meta-QTL (MQTL) analysis was conducted on bread wheat to pinpoint consensus MQTLs for drought tolerance, revealing 13 MQTLs across 6 chromosomes, with the highest concentration on chromosome 5A.
  • The mean confidence intervals for these MQTLs were significantly narrower than those of the original QTLs, suggesting greater precision in identifying genetic markers.
  • Additionally, 228 candidate genes were identified linked to 6 MQTLs, with 14 showing significant expression changes under drought conditions, indicating their potential roles in enhancing drought tolerance through molecular breeding.
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