Association between PM10 exposure and risk of myocardial infarction in adults: A systematic review and meta-analysis.

Background: Air pollution has several negative health effects. Particulate matter (PM) is a pollutant that is often linked to health adversities. PM2.

The 'take-5 theatre brief': Group mindfulness practice for operating theatre teams.

Background: A surgical team works in a high-performance environment and is exposed to stress. Mindfulness practice is evidenced to reduce symptoms of stress, as well as burnout, which is high amongst health workers. The operating theatre is unique, with many job-roles, needs and time-critical tasks.

Frequency of TP53 Mutation in B-Cell Chronic Lymphocytic Leukaemia and its Association with Lymphocyte Doubling Time.

Objective: To determine the frequency of TP53 mutation at diagnosis of B-cell Chronic Lymphocytic Leukaemia (B-CLL) in Pakistani patients, and to investigate whether lymphocyte doubling time (LDT) of less than 1 year could be used as a surrogate marker for TP53 mutation.

Study Design: A cross-sectional descriptive study. Place and Duration of the Study: Department of Haematology, Liaquat National Hospital, from January 2020 to December 2022.

Retrospective on Exploring MXene-Based Nanomaterials: Photocatalytic Applications.

Nanostructural two-dimensional compounds are grabbing the attention of researchers all around the world. This research is progressing quickly due to its wide range of applications in numerous industries and enormous promise for future technological breakthroughs. Growing environmental consciousness has made it vital to treat wastewater and avoid releasing hazardous substances into the environment.

Photocatalytic degradation of industrial dye using hybrid filler impregnated poly-sulfone membrane and optimizing the catalytic performance using Box-Behnken design.

Mixed Matrix Membranes have gained significant attention over the past few years due to their diverse applications, unique hybrid inorganic filler and polymeric properties. In this article, the impregnation of nano-hybrid filler (polyoxometalates (∼POMs) encapsulated into the metal-organic framework (MOF) ∼ PMOF) on the polysulfone membrane (∼PSF) was done, resulting in a mix matrix membrane (∼PMOF@PSF). The developed structure was characterized by Fourier transform infrared (FT-IR), powder X-ray diffraction (PXRD), thermogravimetric analysis (TGA), scanning electron microscopy (SEM), and transmission electron microscopes (TEM).

Removal of persistent acetophenone from industrial waste-water via bismuth ferrite nanostructures.

Increasing water pollution is a severe problem in densely industrialized countries. Nanomaterials provide strong potentials for the efficient elimination of organic pollutants due to their beneficial properties. Advancement in water purification is required to more efficiently remove the emerging organic contaminants, especially in pharmaceuticals wastes such as acetophenone, which shows high solubility in industrial wastewaters.

Diagnosis and Management of Diffuse Large B-Cell Lymphoma: Society of Medical Oncology, Pakistan Society of Hematology, and Pakistan Society of Clinical Oncology Joint Clinical Practice Guideline.

Diffuse large B-cell lymphoma (DLBCL) is the commonest non-Hodgkin lymphoma encountered by hematopathologists and oncologists. Management guidelines for DLBCL are developed and published by countries with high income and do not cater for practical challenges faced in resource-constrained settings. This report by a multidisciplinary panel of experts from Pakistan is on behalf of three major national cancer societies: Society of Medical Oncology Pakistan, Pakistan Society of Hematology, and Pakistan Society of Clinical Oncology.

Effect of Co-Doping on Thermoelectric Properties of -Type BiTe Nanostructures Fabricated Using a Low-Temperature Sol-Gel Method.

In this work, a novel low-temperature double solvent sol-gel method was used to fabricate (Sm, Ce, Gd) and (Sn, Se, I) co-doped at Bi and Te-sites, respectively, for BiTe nanostructures. The phase-purity and high crystallinity of as-synthesized nanostructures were confirmed using X-ray diffraction and high-resolution transmission electron microscopy. The nanopowders were hot-pressed by spark plasma sintering into bulk pellets for thermoelectric properties.

Grazing Affects Bacterial and Fungal Diversities and Communities in the Rhizosphere and Endosphere Compartments of through Regulating Nutrient and Ion Distribution.

Plant-associated endophytic microorganisms are essential to developing successful strategies for sustainable agriculture. Grazing is an effective practice of grassland utilization through regulating multitrophic relationships in natural grasslands. This study was conducted for exploring the effects of grazing on the diversities and communities of bacteria and fungi presented in rhizosphere soils, roots, stems, and leaves of (), based on high-throughput sequencing.

Synthesis of 3D IrRuMn Sphere as a Superior Oxygen Evolution Electrocatalyst in Acidic Environment.

The design of a three-dimensional structure for an Ir-based catalyst offers a great opportunity to improve the electrocatalytic performance and maximize the use of the precious metal. Herein, a novel wet chemical strategy is reported for the synthesis of an IrRuMn catalyst with a sphere structure and porous features. In the synthetic process, the combined use of citric acid and formamide is requisite for the formation of the sphere structure.

Types of paraproteinemia in patients with multiple myeloma: A cross-sectional study.

Objective: To determine the types of paraproteins in patients with multiple myeloma in a tertiary care setting.

Methods: The cross-sectional study was conducted at the Liaquat National Hospital, Karachi, from November 2015 to May 2016, and comprised patients with multiple myeloma selected using consecutive, non-probability sampling technique. Detailed history was taken and immunofixation assay was conducted to assess the type of paraproteins in the patients.

Effect of Graphene Oxide Nano-Sheets on Structural, Morphological and Photocatalytic Activity of BiFeO-Based Nanostructures.

Photocatalysts are widely used for the elimination of organic contaminants from waste-water and H evaluation by water-splitting. Herein, the nanohybrids of lanthanum (La) and selenium (Se) co-doped bismuth ferrites with graphene oxide were synthesized. A structural analysis from X-ray diffraction confirmed the transition of phases from rhombohedral to the distorted orthorhombic.

Influence of Zn Doping on Ni-Based Nanoferrites; (Ni ZnFeO).

Nickel zinc nanoferrites (NiZnFeO) were synthesized via a chemical co-precipitation method having stoichiometric proportion (x) altering from 0.00 to 1.00 in steps of 0.

Influence of Refractive Index on Antireflectance Efficiency of Thin Films.

In today's world, scientific development is tremendously strengthened by imitating natural processes. This development remarkably validates progressive and efficient operation of multifunctional thin films in variable ecological circumstances. We use TFCalc thinfilm software, a reliable and trustworthy simulation tool, to design antireflective (AR) coatings for solar cells that can operate in varying environmental conditions and can be functional according to user-defined conditions.

Disease staging according to international scoring system in newly diagnosed patients with multiple myeloma.

Objective: To determine the frequency of disease staging according to international scoring system in patients who are newly diagnosed with Multiple Myeloma (MM) at a tertiary care hospital at Karachi.

Methods: This single center, non probability consecutive, cross sectional study was conducted from Nov 11, 2015 to May 11, 2016. After taking informed written consent, detailed history was taken and serum β2 microglobulin and albumin levels were checked to assess the study outcome variable i.

Institutional-based tumor registry of hematopoietic malignancies: A 4 years' preliminary report from Karachi.

Background: Pakistan has a population of over 198 million making it the world's sixth populous country. However, operational population-based cancer registries in Pakistan are lacking. Limited data are available based on institutional or Karachi Cancer Registry from Karachi; however, no exclusive registry for hematological malignancies is established till date.

Internal quality control of blood products: An experience from a tertiary care hospital blood bank from Southern Pakistan.

Introduction: Internal quality control (IQC) is the backbone of quality assurance program. In blood banking, the quality control of blood products ensures the timely availability of a blood component of high quality with maximum efficacy and minimal risk to potential recipients. The main objective of this study is to analyze the IQC of blood products as an indicator of our blood bank performance.

Pattern of bone marrow involvement in non Hodgkin's lymphoma classified according to WHO classification: Report of a developing country Pakistan.

Background: Limited information is available from developing countries in patients of non-Hodgkin's lymphoma (NHL). Hence, we reviewed the demographical profile along with bone marrow infiltration pattern in patients with NHL presented at Liaquat National Hospital and Medical College.

Materials And Methods: In this descriptive study, adult patients with NHL were enrolled from January 2011 to December 2015.

Strong convergence of gradient projection method for generalized equilibrium problem in a Banach space.

In this paper, we propose and analyze a hybrid iterative method for finding a common element of the set of solutions of a generalized equilibrium problem, the set of solutions of a variational inequality problem, and the set of fixed points of a relatively nonexpansive mapping in a real Banach space. Further, we prove the strong convergence of the sequences generated by the iterative scheme. Finally, we derive some consequences from our main result.

Clinico-hematological Profile of 184 Patients with Non-Hodgkin's Lymphoma: An Experience from Southern Pakistan.

Background: Non-Hodgkin lymphoma (NHL) is a diverse group of lymphoma comprises of divergent tumors with paradoxical clinical behaviors and potential difference in response to therapy. We conducted a data-base analysis on NHL patients to evaluate the clinico-epidemiological features and WHO spectrum of NHL in Pakistani patients.

Materials And Methods: This descriptive study was conducted over a period of 5 years from January 2011 to December 2015 at Hematology department of Liaquat National Hospital.

Insight into donor deferral pattern based on peripheral blood counts: An experience from South Pakistan.

Background: Donor deferral owing to anemia is one of the major causative factors of temporary donor rejection, which is preventable and treatable. The basic knowledge about frequency, types, and severity of anemia among donors will help plan a strategy to promote donor recruitment and overall national health.

Objective: The objective of this study was to provide the predonation deferral rate of the healthy blood donors based on peripheral blood counts and second to determine the types of anemia along with its severity.

In Vitro Leukoagglutination: A Rare Hematological Cause of Spurious Leukopenia.

Leukopenia secondary to leukocytic agglutination is caused by an ethylene diamine tetra acetic acid (EDTA) which may appear in both benign and malignant states. Ethylene diamine tetra acetic acid induced platelets clumping in peripheral blood has been well established, but invitro leukocytic aggregation is very rarest hematological finding. Pseudo-leukopenia resulting from leukoagglutinins has been reported in the cirrhotic state, infections, autoimmune disorders, uremia, in immunosuppressed state or in various malignancies.

Pattern of Karyotypic Aberrations in Pakistani Patients with De Novo Acute Myeloid Leukemia.

Background: Acute myeloid leukemia (AML) is a malignant disease of the bone marrow in which karyotypic analysis is the most important diagnostic and prognostic tool for predicting remission rate, relapse and overall survival. This study was carried out to determine the frequency and type of cytogenetic aberrations in de novo acute myeloid leukemia in adults at a tertiary care hospital.

Materials And Methods: This descriptive cross-sectional study was carried out in the Hematology Department, Liaquat National Hospital from November 2014 to April 2016.