Publications by authors named "Irfan R Khan"
Purpose: To evaluate dexamethasone intravitreal implant effectiveness in lieu of high-dose oral prednisone for short-term treatment of noninfectious intermediate and posterior uveitis in patients requiring immunosuppression.
Methods: This is a proof-of-concept, open-label, non-comparative clinical trial with 12-month follow-up. The primary outcome was uveitis control without additional prednisone at 6 and 12 months.
Purpose: To quantitate the risk of relapse of ocular and extraocular disease among patients with mucous membrane pemphigoid (MMP) who had undergone drug-free remission.
Design: Retrospective, comparative, interventional case series.
Methods: There were 167 patients with biopsy-proven MMP who were seen at the Wilmer Eye Institute between November 1984 and December 2019.
: To describe the risk of developing ocular mucous membrane pemphigoid (MMP) or a new extraocular site of MMP, and to identify risk factors for new involvement. : Retrospective chart review of 162 biopsy-proven MMP patients. : At presentation, 109 of 162 MMP patients (67.
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- The study analyzed 96 patients with retinal vasculitis to assess the rates of visual loss and ocular complications over a median follow-up of 44 months.
- Findings indicated that the overall rates of visual loss were relatively low, with certain complications like cataracts and epiretinal membranes being more common among patients.
- Patients with a relapsing disease course faced a higher risk of visual loss, although treatment with immunosuppressive drugs significantly reduced this risk.