Publications by authors named "Iretiola Bamikeolu Fajolu"

Article Synopsis
  • Surrogacy in Nigeria allows couples facing infertility to have children through a surrogate who carries the pregnancy, gaining popularity compared to adoption.
  • There are two types of surrogacy: gestational, where embryos are created via IVF, and traditional, using the surrogate's own egg; however, it presents challenges including medical, ethical, and legal issues impacting the newborns.
  • The case report of preterm triplets emphasizes the necessity for better regulation in surrogacy practices, as challenges included feeding issues, lack of appropriate care, and obtaining necessary legal consents for the infants.
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Introduction: Inappropriate use of antibiotics for childhood illnesses, especially for non-bacterial infections, contributes to the development of antimicrobial resistance (AMR). Globally, implementation of antimicrobial stewardship programme (ASP) in all healthcare institutions is a strategic intervention to improve the appropriate use of antibiotics, reduce antimicrobial consumption and tackle AMR. The aim of this study was to evaluate the effect of prospective audit with intervention and feedback as an antimicrobial stewardship strategy on antimicrobial use, evaluate prescribers' response to recommendations and determine the rate of AMR in the Paediatrics Department of the Lagos University Teaching Hospital, Nigeria.

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Background: Neonatal mortality accounts for approximately 46% of global under-5 child mortality. The widespread access to mobile devices in low- and middle-income countries has enabled innovations, such as mobile virtual reality (VR), to be leveraged in simulation education for health care workers.

Objective: This study explores the feasibility and educational efficacy of using mobile VR for the precourse preparation of health care professionals in neonatal resuscitation training.

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Article Synopsis
  • Neonatal mortality significantly contributes to under-five mortality rates in Nigeria, which has the second-highest neonatal death toll globally.
  • A study at Lagos University Teaching Hospital reviewed neonatal admissions from January 2018 to April 2020, revealing a 17.6% mortality rate with common diagnoses including neonatal jaundice, infections, and prematurity complications.
  • The findings emphasize the need for enhanced neonatal care, particularly in respiratory support and public education about neonatal jaundice to reduce mortality rates.
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Objective: To assess the impact of mobile virtual reality (VR) simulations using electronic Helping Babies Breathe (eHBB) or video for the maintenance of neonatal resuscitation skills in healthcare workers in resource-scarce settings.

Design: Randomised controlled trial with 6-month follow-up (2018-2020).

Setting: Secondary and tertiary healthcare facilities.

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Introduction: approximately 1 million children die each year due to complications of preterm birth with the major contributor to mortality being hypothermia. Kangaroo mother care (KMC) is an effective and low-cost technique which prevents neonate from hypothermia. The mother uses her body temperature to keep the infant warm thereby preventing demise from cold injury.

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The COVID-19 pandemic is currently causing widespread infection and deaths around the world. Since the identification of the first case in Nigeria in February 2020, the number of confirmed cases has risen to over 9,800. Although pregnant women are not necessarily more susceptible to infection by the virus, changes to their immune system in pregnancy may be associated with more severe symptoms.

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Article Synopsis
  • - The study investigated the prevalence of an unspecified infection among malnourished children and its association with socioeconomic and clinical factors, involving 122 malnourished children and 120 healthy controls.
  • - Results showed that 22.8% of malnourished children had the infection compared to 32.5% in healthy controls, with a notably higher prevalence in toddlers and a significant link to low socioeconomic status and stunting.
  • - The conclusion emphasized the need for screening malnourished children for the infection and highlighted the importance of further research on the socioeconomic factors related to the infection.
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Background: Lead toxicity is a cause of intellectual disability in children and majority of affected children live in developing countries. Its adverse effect on pregnancy outcome has also been documented.

Objectives: To assess the relationship between maternal blood lead levels and umbilical cord blood lead levels in their corresponding newborn infants; to determine factors associated with high blood lead levels and the pregnancy outcome in participants.

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Introduction: Human immunodeficiency virus and protein energy malnutrition are still prevalent in Nigeria and the occurrence of the two conditions together confers a poor prognosis. The aim of this study was to determine the current categories of malnutrition amongst under-5 children in Lagos, document their HIV status and determine any peculiarities in the clinical features, haematological and some biochemical profile in these children.

Methods: The study was a cross-sectional study conducted at the Paediatric departments of the Lagos University Teaching Hospital and the Massey Street Children's Hospital, both in Lagos, over a 6-month period.

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Background And Objectives: Sick neonates in malaria endemic areas are frequently transfused with donor blood unscreened for malaria parasite. Consequently, they are at risk of transfusional malaria which can lead to increased neonatal mortality. The study aimed to determine the burden of transfusional malaria in neonates to help in policy formulation on prevention of transfusional malaria.

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Background: Invasive candidiasis has been identified globally as a major cause of morbidity and mortality in neonatal intensive care units (NICU). Systemic candidiasis presents like bacterial sepsis and can involve multiple organs.

Objective: The objective of this study was to determine the prevalence of Candida infection in a NICU at a tertiary hospital in Nigeria and to identify its associated risk factors.

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Background: In 2008, several Nigerian children developed acute kidney injury (AKI) after ingesting teething syrup contaminated with diethylene glycol (DEG). Because there are limited diagnostic facilities in resource-constrained countries, this study investigated whether AKI associated with DEG could be identified by other means.

Methods: This was a multicenter study.

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