Background: The aim was to estimate the risk of subsequent extra-cervical Human Papillomavirus (HPV) related cancer in patients surgically treated for high grade cervical intraepithelial neoplasia (CIN 2-3). This is the first study in Italy investigating the occurrence of extra-cervical tumors in this cohort of patients.
Methods: 3184 patients surgically treated for CIN2-3 since 1992 at the Department of Surgical Sciences of University of Torino were considered.
Over a period of a few years, Cancer registries in North Africa (Morocco, Algeria, Tunisia, Libya, Egypt) increased in number from one to seven. Currently they serve 9.7% of the total regional population.
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