Effect of recombinant growth hormone treatment on children with Crohn's disease and short stature: a pilot study.

Background: Growth failure frequently complicates Crohn's disease in childhood. Abnormalities in the growth hormone (GH)/insulin-like growth factor-1 axis may occur. The effects of administered GH on growth have not been studied previously in a randomized trial.

Value of rectosigmoidoscopy with biopsies for diagnosis of inflammatory bowel disease in children.

Background: In children with inflammatory bowel disease (IBD), treatment depends on the type and extent of disease. Therefore, maximal effort should be made to provide a correct diagnosis. The aim of this study was to assess the value of a histologic diagnosis made on the basis of either ileal and colonic or rectosigmoid biopsies.