Publications by authors named "Irene Rosa-Perez"
Article Synopsis
- * The study conducted at the University Hospital La Paz analyzed the genetic basis of keratoconus in 24 pediatric families using whole-exome sequencing, finding an oligogenic inheritance pattern.
- * Identified candidate genes are linked to various corneal functions and repair processes, indicating potential therapeutic targets, but further research is needed to validate their role in pediatric keratoconus.
Article Synopsis
- Early-onset high myopia (EoHM) is defined as having significant refractive errors before the age of 10, leading to various eye issues.
- A study involving 43 families with EoHM was conducted, where genetic analysis revealed that 23.9% of families had detectable pathogenic variants, while 76.1% had variants of unknown significance.
- The research highlights the need for comprehensive genetic testing in EoHM cases to improve patient management, prognosis, and genetic counseling efforts.
To describe a standardized protocol of the dexamethasone intravitreal (DEX) implant Ozurdex (Allergan, Dublin, Ireland) performed in a controlled environment surgical cabin (CESC). Retrospective and observational study conducted on patients who underwent a DEX implant between May 2011 and June 2019, in a third level University Hospital. The controlled environment surgical cabin (ArcSterile, Imex, Valencia, Spain) used in this study was the MB 20 (2 m width, 1.
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