Reliability and economic assessment of the Multiplex® optical sensor employed for non-destructive grape parameters estimates was evaluated in 2017 against a wet chemistry approach in mature vineyards including five cultivars (two whites, two red and one pink colored) assuring a broad range of variation in both technological and phenolic maturity parameters. Among the five Multiplex (Mx) indices evaluated (SFR_R, FLAV, FLAV-UV, ANTH_RG and FERARI) in all cultivars with the exception of Barbera SFR_R showed a significant and linear correlation with total soluble solids (TSS) for TSS ≥ 10 °Brix. Conversely, no significant correlation was found between FLAV and total flavonols concentration, whereas a significant linear correlation was found in Barbera (R2 = 0.
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