Publications by authors named "Irene Ramos-Lopez"
Article Synopsis
- - Inflammation plays a critical role in age-related diseases, particularly neurological conditions like Alzheimer's Disease and other neurodegenerative disorders, significantly impacting healthcare as the population ages.
- - The research highlights that targeting inflammation may mitigate Abeta proteotoxicity, with drugs like Humira demonstrating the commercial potential of anti-inflammatory treatments.
- - High-throughput screenings identified compounds such as phenylbutyrate, methicillin, and quetiapine as effective at reducing Abeta proteotoxicity, suggesting that existing drug classes may offer promising avenues for treating age-related neurodegenerative diseases.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated clinical syndrome COVID-19 are causing overwhelming morbidity and mortality around the globe and disproportionately affected New York City between March and May 2020. Here, we report on the first 100 COVID-19-positive autopsies performed at the Mount Sinai Hospital in New York City. Autopsies revealed large pulmonary emboli in six cases.
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