Metabolic diagnosis in stone formers in relation to body mass index.

It is known that several metabolic abnormalities that favor stone formation have a strong dependence on environmental and nutritional factors. The incidence and prevalence of kidney stone is increasing while there has been a parallel growth in the overweight/obesity rate, and epidemiologic studies have shown a significant association between overweight/obesity and increased nephrolithiasis risk. The aim of this study was to assess if metabolic abnormalities observed in stone patients differ in relation to their BMI.

Role of overweight and obesity on the urinary excretion of promoters and inhibitors of stone formation in stone formers.

In recent decades there has been an increasing prevalence of urolitithiasis in many western countries and at the same time there has been an increasing progression of obesity that has reached epidemic proportions. The aim of the present study was to assess the influence of overweight/obesity on the metabolic risk factors for renal stone formation. We studied 799 renal stone formers (462 men and 337 women) who came to the clinic for metabolic risk factors evaluation.

Clinical and biochemical profile of patients with "pure" uric acid nephrolithiasis compared with "pure" calcium oxalate stone formers.

The purpose of the present study was to compare the clinical characteristics of "pure" uric acid (UA) stone formers with that of "pure" calcium oxalate (CaOx) stone formers and to determine whether renal handling of UA, urinary pH, and urinary excretion of promoters and inhibitors of stone formation were different between the two groups. Study subjects comprised 59 patients identified by records of stone analysis: 30 of them had "pure" UA stones and 29 had "pure" CaOx nephrolithiasis. Both groups underwent full outpatient evaluation of stone risk analysis that included renal handling of UA and urinary pH.

Prevalence of urolithiasis in the autonomous city of Buenos Aires, Argentina.

Urolithiasis is the third most common pathological disease afflicting the urinary tract, and usually occurs between the third and fourth decades of an individual's life. Epidemiological studies about this condition are lacking in our country. In 1998, we performed an epidemiological, cross-sectional study of the prevalence of urolithiasis in a sample of 1,086 subjects, which included men and women of all ages, selected from the general population of the city of Buenos Aires.