Publications by authors named "Irene Perez-Moreno"
Article Synopsis
- Male mouse meiosis research has relied on invasive methods that require sacrificing animals to observe meiocytes, often involving drug administration that raises animal welfare concerns.
- New approaches have emerged, focusing on in vitro techniques that reduce animal use and improve ethical standards in research.
- A validated organotypic culture method for seminiferous tubules is recommended as an effective alternative, preserving tissue structure and allowing for varied experimental conditions without compromising animal welfare.
Introduction: Critically ill patients typically develop a catabolic stress state as a result of a systemic inflammatory response (SIRS) that alters clinical-nutritional biomarkers, increasing energy demands and nutritional requirements.
Objective: To evaluate the status of albumin, prealbumin and transferrin in critically ill patients and the association between these clinical-nutritional parameters with the severity during a seven day stay in intensive care unit (ICU).
Method: Multicenter, prospective, observational and analytical follow-up study.
Background: trauma and severe infections cause remarkable metabolic changes in patient with SIRS from an adaptive response aimed to control the underlying disease, repairing damaged tissue, and to synthesize substrates. If the attack is intense and sustained and the patient has a compromised nutritional status, can evolve into multiple organ failure and death.
Objective: assessment of nutritional proteic status and the involvement of proteins and inflammatory factors in critically ill patients.