Publications by authors named "Irene Macaya"
Purpose: Assess the impact of viral load estimated by cycle threshold (Ct) of reverse transcription real time-polymerase chain reaction (rRT-PCR) and the days from symptoms onset on mortality in hospitalized patients with COVID19.
Methods: Retrospective observational study of 782 patients with a positive rRT-PCR from a nasopharyngeal swab was performed within the first 24 h from admission. Demographic data, clinical manifestations and laboratory parameters were collected.
Importance: Identifying undetected clinical signs is imperative in the prevention of SARS-CoV-2.
Objective: To establish the prevalence of clinical gustatory and olfactory dysfunctions in patients with COVID-19 pneumonia. Clinical outcomes and recovery rates associated with gustatory and olfactory dysfunctions were also assessed.
Article Synopsis
- The study investigated how treatments like anti-IL-6 biologics and corticosteroids affect the risk of hospital-acquired infections in COVID-19 patients.
- A case-control framework was used, comparing 71 COVID-19 patients with infections to 142 matched controls without infections.
- Key findings highlighted that severe comorbidities, like chronic liver disease and invasive mechanical ventilation, dramatically increased infection risk, while inflammatory response modifiers showed no impact on hospital-acquired infections.
Objectives: To describe the burden, epidemiology and outcomes of co-infections and superinfections occurring in hospitalized patients with coronavirus disease 2019 (COVID-19).
Methods: We performed an observational cohort study of all consecutive patients admitted for ≥48 hours to the Hospital Clinic of Barcelona for COVID-19 (28 February to 22 April 2020) who were discharged or dead. We describe demographic, epidemiologic, laboratory and microbiologic results, as well as outcome data retrieved from electronic health records.