Proton observed phosphorus editing (POPE) for in vivo detection of phospholipid metabolites.

The purpose of this article was to compare the sensitivity of proton observed phosphorus editing (POPE) with direct (31) P MRS with Ernst angle excitation for (1) H-(31) P coupled metabolites at 7 T. POPE sequences were developed for detecting phosphocholine (PC), phosphoethanolamine (PE), glycerophosphocholine (GPC), and glycerophosphoethanolamine (GPE) on the (1) H channel, thereby using the enhanced sensitivity of the (1) H nuclei over (31) P detection. Five healthy volunteers were examined with POPE and (31) P-MRS.

Tilt optimized flip uniformity (TOFU) RF pulse for uniform image contrast at low specific absorption rate levels in combination with a surface breast coil at 7 Tesla.

Purpose: Going to ultrahigh field MRI (e.g., 7 Tesla [T]), the nonuniformity of the B1+ field and the increased radiofrequency (RF) power deposition become challenging.

Adiabatic turbo spin echo in human applications at 7 T.

Nonuniform B(1) fields in ultrahigh-field MR imaging cause severe image artifacts, when conventional radiofrequency (RF) pulses are used. Particularly in MR sequences that encompass multiple RF pulses, e.g.