Publications by authors named "Irene Lirio"
Article Synopsis
- Rhinoviruses (RVs) are common causes of severe respiratory infections in hospitalized children, categorized into three species: RV-A, RV-B, and RV-C, with RV-C further divided into several clades.
- A study in rural Philippines examined clinical data from children under 5 years old, revealing 713 cases of RV infections among 3680 respiratory illness episodes, predominantly RV-C.
- The findings indicated that children with RV-C, especially the GAC1 clade, experienced more severe respiratory symptoms compared to those infected with RV-A or RV-B, highlighting RV-C's role in severe illnesses.
Background: Lower respiratory tract infection (LRTI) is an important cause of morbidity and mortality in infants and young children. However, the etiological role of viruses and the timing of developing LRTI are not well defined.
Methods: We analyzed the data of a prospective cohort study in the Philippines as a birth cohort.
Background: Human respiratory syncytial virus (RSV) is the leading cause of severe acute respiratory infection in infants and young children, which is characterized by repeated infections. However, the role of amino acid substitutions in repeated infections remains unclear. Hence, this study aimed to elucidate the genetic characteristics of RSV in children with repeated infections using molecular analyses of F and G genes.
View Article and Find Full Text PDFBackground: Human respiratory syncytial virus (HRSV) is a leading viral etiologic agent of pediatric lower respiratory infections, including bronchiolitis and pneumonia. Two antigenic subgroups, HRSV-A and B, each contain several genotypes. While viral load may vary among HRSV genotypes and affect the clinical course of disease, data are scarce regarding the actual differences among genotypes.
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